so um… you know how people say if you stop exercising, your muscle becomes fat?

well… today, i found out that’s literally possible.  apparently C2C12 cells can “transdifferentiate” to adipocytes if you prevent its differentiation to muscle cells (e.g. getting rid of myoD). @___@.  one of today’s talks also showed you can actually not only transdifferentiate it to adipocytes, but you can also transdifferentiate it into brown adipocytes if you also knock-down PPAR-gamma in the cells. what.

though i’m not sure what the implications of that are really, because you’d think that from a metabolic standpoint, muscle is still better than any type of fat, brown or not…

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